This study examined the impact of instructional supervision on secondary school students’ academic performance in English Language. Descriptive method was adopted in which a questionnaire titled Instructional Supervision and Students’ Academic Performance Questionnaire (ISSAPQ) was administered to obtain data from sixty teachers from the three senatorial districts in the state, while the performance of the students in English Language was obtained from the 2008 Senior Secondary School Certificate Examination(SSCE) result of the sixty randomly sampled schools . Simple random techniques were used accordingly to select the sampled teachers. Pearson product moment correlation was used to answer the question. The null hypotheses were tested at 0.05 significant level. The study showed that there were significant impacts of checking of students’ notes, class visitations, checking of teachers’ punctuality and attendance and moderation of examination questions and marking scheme on students’ academic performance in English Language in Senior Secondary Schools in Ondo State. Recommendations for checking of students notes by school principals were made.